Vaisesika Sūtra 7.1.10

अतो विपरीतमणु ॥१०॥

ato viparītam-aṇu ॥10॥

[अतः (ataḥ) - therefore; विपरीतम् (viparītam) - opposite extreme; अणु (aṇu) - minute particle;]

Therefore, the minute particle is the opposite extreme.