Vaisesika Sūtra 1.1.17

eka-dravyam-aguṇaṁ saṁyoga-vibhāgeṣu anapekṣa-kāraṇam iti karma-lakṣaṇam ॥17॥

A single substance is without qualities, and is independent of the cause, by its combination and disjunction. This is the characteristics of movement (karma).