Yōga Sūtra 1.40

परमाणुपरममहत्त्वान्तोऽस्य वशीकारः।

From it comes the control (vashikar) over the smallest of small particles, and the highest of higher principles.

Understanding the smallest of small particle and biggest of big phenomenon is always considered as complete knowledge in Indian philosophy (Ref Ishawasya Upanishad). With the practice of meditation consciousness becomes capable of grasping these phenomena. It is interesting to note, even today physicists are struggling to understand these phenomena and have no conclusive answers. The particles with which dark-matter is made up of, and how big-bang arouse from singleton are still not understood.